Alpha Medical Lab
Clostridium difficile Culture with Reflex to Toxin B, Real-Time PCR,Isolate
Ordered Test Code:
CDIFFCUL
| Lab Test Component | Requirement |
|---|---|
| Test Name | Clostridium difficile Culture with Reflex to Toxin B, Real-Time PCR,Isolate |
| Alpha’s Order Test Code | CDIFFCUL |
| Specimen Collection Tube | Sterile Cup/5 grams or 5mL |
| Collection Tube Handling | |
| Minimum Volume | 2 gram or 2mL |
| Transport Temperture | Frozen |
| Stability | Room temperature: Not acceptable; Refrigerated: 48 hours; Frozen -20° C: Not established; Frozen -70° C: 7 days |
| Collection Instructions | Toxin is heat labile. Freeze as soon as possible. Submit frozen stool in sterile screw-cap container. |
Clinical Significance
C. difficile causes 50-75% of antibiotic associated colitis and greater than 90% of antibiotic associated pseudomembranous colitis. Pathogenic C. difficile produce two potent toxins, toxin A and toxin B, that cause diarrhea and colitis.
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